Antigenic Shift and the H1N1 Influenza A Virus

Published 2020-01-30
Antigenic Shift and the H1N1 Influenza A Virus
This animation provides an overview of the principles of antigenic shift and the H1N1 influenza A virus. One way influenza viruses change is called “antigenic shift” (the other is “antigenic drift”.) Antigenic shift is an abrupt, major change in an influenza A virus, resulting in new HA and/or new HA and NA proteins in influenza viruses that infect humans. Shift can result in a new influenza A subtype in humans. One way shift can happen is when an influenza virus from an animal population gains the ability to infect humans. Such animal-origin viruses can contain an HA or HA/NA combination that is so different from the same subtype in humans that most people do not have immunity to the new (e.g., novel) virus. Such a “shift” occurred in the spring of 2009, when an H1N1 virus with genes from North American Swine, Eurasian Swine, humans and birds emerged to infect people and quickly spread, causing a pandemic. When shift happens, most people have little or no immunity against the new virus.

All Comments (19)
  • I had H1N1 in 2010 in Oklahoma I had never felt so sick ever in my life I remember I couldn’t get off my couch and had a fever all day and the next day I was so weak I could barley hold a cup in my hand but after 5 days I started feeling better and after 3 weeks I was ok it very fkn scary
  • @MrAvGeekMan
    I like how you explain deadly microscopic organisms even though I'm not a scientist.
  • @Jojo-hh6ru
    Who else came here after COVID-19 got announced as a pandemic....😭
  • @sentosaco
    Have no idea what this means, I just fled here from the COVID-19 pandemic.
  • You know he knows how to teach, when u failed in biology in 9th grade but still understand this. Kinda
  • @Ccscenario
    I had H1N1 when I was a kid probably when I was 4 or 7 can’t remember since I was really sick and was put on a ventilator, right now I’m 15 years old I was wondering if H1N1 has long term affects because for a while of my child hood I had asthma but when I grew older it just slowly went away but in place of my asthma I have severe allergies like dust pollen and all of that.
  • @fadrium1464
    All you need is the wrong bat meet the wrong Pig. Then voila new pandemic.
  • @davejames2015
    I had this, couldn't keep anything down, shit myself stupid. Felt like I was going to die. Went to the emergency and they shoved a thing up my nose then sent me home. Was better in a few days, meaning I could keep food down. hopefully the covid 19 isn't worse than this one. Don't know if the hearts got another round in it.
  • @Baghuul
    This is probably a stupid question. Can a cell be infected with both a flu virus and coronavirus and then share genetic material?
  • @anachavez661
    Their are thousands of microbiomes in the human stomach that help fight off the microbiomes from animals
  • @dantheman9852
    So it came from birds to people to pigs and then back to people in a worse form? 🤔 doesn't sound right with out intentional human involvement. 😕