Sickle Cell Disease by V. Tran, N. Archer | OPENPediatrics

Published 2023-06-09
By the end of this video, the learner will be able to describe the fundamental elements of sickle cell disease, including pathophysiology, potential complications, and management strategies.
0:00 Introduction
3:18 Pathophysiology
5:06 Complications
9:13 Management
15:13 Summary

LEARNING OBJECTIVES
By the end of this video, the learner will be able to:
• Describe the fundamental elements of sickle cell disease
• Discuss the pathophysiology of sickle cell disease
• Identify the common complications seen in this condition
• Describe the management options for sickle cell disease and its complications

AUTHORS
Virginia Tran, BS
Harvard Medical School

Natasha Archer, MD
Physician
Dana Farber/Boston Children's Cancer and Blood Disorders Center
Assistant Professor of Pediatrics
Harvard Medical School

DATES
Initial publication: June 9, 2023

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CITATION
Tran V, Callas C, Moulton H, Fantasia K, McFee AM, Wolbrink TA, Archer N. Sickle Cell Disease. 06/2023. OPENPediatrics.    • Sickle Cell Disease by V. Tran, N. Ar...  .

All Comments (5)
  • @Rene-uz3eb
    6:45 a higher calcium diet in rats delayed hypertrophy. Bp medication made it worse. Careful though: large intake will result in more urinary calcium, effected by calcitonin, and the precalcitonin levels are used to diagnose serious infections. So calcium intake right before a blood test should be avoided
  • Please stop telling providers the genotype HbSC is “ milder” by the time a person reaches adulthood it all becomes severe
  • @Praise_ye_Yahweh
    I find the video very helpful, but the mutation occurs on the 11th chromosome, not the 6th chromosome.