Parkinson's disease "What do successful people do to slow down PD progression?” Dr. Laurie Mischley

I was diagnosed with PD about three years ago with tremors as my initial symptom. I have read every paper and examined all the other anecdotal and scientific material I could find. Armed with this information I conducted a series of strategies designed to mitigate the symptoms and slow the progression of PD in my case. The result is that my tremors remain largely unchanged but my quality of life has increased dramatically. I exercise regularly, walking and resistance training. This has paid significant dividends in my stamina and also my general robustness. Of all the various supplements I've tried, creatine monohydrate has had the most noticeable benefits, further contributing to my stamina and also (subjectively) improving my clarity of thought. Reducing my intake of carbohydrates (albeit I'm not on a keto diet) has had a small but measurable positive effect as well. One thing I decided not to do was to start taking levadopa too soon. Although I do take it when I absolutely need to be able to use my hands tremor-free, that's usually no more than once or twice a month. As a result, I'm not on the wagon of having to regularly hike the dose. I have developed a mountain of "coping strategies" to deal with the tremors, the falls, the distonia and the sleep disturbances -- to the point that I am now happier, fitter, stronger and feel healthier than I was five years ago. Nothing will stop the progression of my PD but it feels empowering to be able to put up the strongest fight I can and so far I'm doing very well.

Surprised she did not mention the Keto diet for Parkinsons in comparing diets

Dr Laura M has been a light in the dark times since diagnosis. Thank you for all the positivity and inspiration!

Dr Laurie Mischley, you rock! So sad. Doctors today aren't like you. You are 💯 right. People need to take more responsibility for their own health and wellness. There are many solutions available if only we seek them. God Bless you and yours always❤

Of all the videos you have done I found this one probably the most interesting, watched it 3 times. I am 74, Diagnosed 6 yrs ago and Med free so far, tremor dominant. For some reason from the beginning I went on a Keto diet, dropped 30Lbs which I needed to do aanyway. The point of writing is to say I have been experimenting with food and this vid has given me the encouragement to do more of it. I also have been on 1000MG of B1 per day from the start.. I find Dr M very easy to listen to and will follow her closely.Please interview her again in the not to distant future.

ThxU I’m been trying navigate myself since 2016 I’m 55yrs indigenous female struggling no support between my neurologist and GP I’m just a number and still trying to do my best to get through the Pain, Falls, Insomnia, Dyskinesia, Constipation, Stiffness, Confusion in everyday tasks, Involuntary movements, Diet very poor because of being displaced You given me the encouragement to not give up that watching your videos and others on Parkinson Disease is my only hope to get through another day and remain positive!! ThxU ThxU 🙏🏼💜😊

My wife just got diagnosed and I am freaking out. I am trying to learn all I can and this is far above all other videos I have seen on information.. thank you so much

Bit puzzled to hear that sugar isn't so bad for pd 🤔(minute 53 in the vid )

Excellent! I was diagnosed 1 year ago at age 56. I have been very suspicious that the healthcare system treating this disease is very fragmented and seems to mentally prepare you for the worst. I am now learning and experiencing that I have options that dramatically improve my symptoms. I will be signing up for any studies you have. Thank you!!

The solution is so simple. I'm on carnivore (dr Berry on youtube ) a year and B1 (under tongue on Amazon 7$, Elliott Overton on Youtube) and no more walker and yesterday did 5 thrift stores in the aft! Impossible 6 years ago. I can think straight again and follow a movie. I'm 78 and aging in reverse. My Parkinson's has halted and reversed. I still have slight morning tremor and take one Levaddopa in the morning and that is ALL. I'm not exercising but need to get back to walking. Neurologist discharged me as doing fine.

So happy to hear some positivity 4 a change❤

Excellent discussion. I think you conflated the Rivastigmine patch (Exelon, acetylcholinesterase inhibitor, used for dementia) with Rotigotine patch (Neupro, a dopamine receptor agonist for PD or RLS). Also, I check homocysteine (a waste product of levodopa metabolism) in PD patients - it goes up before the B-12 level drops. I take opicapone (Ongentys 50 mg QD) in the morning, not at bedtime, to reduce hypnopompic hallucinations, with much improvement. Keep up the great work! David L. Keller, MD (disabled)

Great, comprehensive presentation on nutrition, research, science and PD. Thank you !

I looked at the assortment of variables with great interest. It seems to me that there is some--not entirely--confusion between correlation and causation. Let us say, for example, that I said men who shaved every day don't get Parkinson's. But men who don't shave do. Well, it seems likely that the men who shave everry day do so in part because they don't have major problems with hand tremors. But the Parkinson's patients with bad hand tremor would maybe wear a beard or shave less often. It has nothing to do with the mechanism of Parkinson's. I don't want to go through all the variables one by one, but it it does seem to me that Dr. Mischeley's emphasis on a social life as diminishing Parkinson's is one such confusion between correlation and causation. If I have bad Parkinson's, my friends might invite me over less (due to the problems of getting me in and out of the house) and frankly they may be uncomfortable with the reminder of mortality. This is unfortunate because some people will feel bad (I should have had more friends) and feel like their disease progression is their fault. Other variables may be interactive--for example, Mischeley et al find no particular effect with sugar, but that could be in the methodology. Half the people "below the line in the good zone" are exercising and therefore better metabolizing sugar (it's well known walking is good for diabetics). The non-exercising group may indeed be taking a hit to their health from sugar. So this kind of data needs to be used with care, I'm not sure everyone who looks at will take the time to sort it out.

Thanks for this great video interview... lots of useful informations! But Michel, can you please speak a little bit slower, because for people like me not fluent in english it is hard to understand what you say 🙂

No more wheel chair use for down town travels. Spent seven months in and out of hospitals for paralysis of my legs. Started Parkinson’s leading medication how ever did not improve my very slow walking. Started Vit B1 100mg twice morning with magneisium 250mg in morning. With two days I went for a three walk none stop, where as only two days be I could bare move one foot in front of the other. The base spine nerve pain is now gone. The nerve pain was a constant remainder that I could drop to the ground at any moment. Try it as it will change your life. Thank you.

This is a highly recommended presentation with lots of insight into the relationship between Parkinson and food and convinced me to radically change my diet! Thank you very much and continue this great work please! I would love to receive the presentation --- where can I find it?

I loved that! Thanks a lot for the work you're all doing! The speaker was amazing! This channel is really awesome!!

This was helpful on so many levels. Thank you for sharing it and for all your efforts. Greatly appreciate your work.

Thank you for your information, I have been affected with PD for 6 years and changed my diets and it has help