Cancer-busting vaccines are coming: here's how they work

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Published 2024-03-27
Most vaccines work by teaching the immune system to recognize harmful viruses or bacteria before a person gets infected and becomes unwell. A few cancer vaccines do this, too. For example, a vaccine is given to young people as protection against human papillomaviruses that can cause cervical cancer.

But scientists are also developing cancer vaccines that could be used as treatments, after cancer has been found.

These vaccines work by teaching the body's immune system to distinguish between healthy cells and abnormal cancer cells. To do this, researchers need to identify proteins that are made by cancer cells but not by healthy cells. These proteins can be used like a barcode. The vaccine teaches the body's immune cells to 'read' the barcode, as a way of identifying the cancer. This video explains how these vaccines are made, and the pros and cons of various types of cancer vaccine.

Read more here: nature.com/collections/cancer-vaccines-outline

This Nature Video is editorially independent. It is produced with third party financial support. Read more about Supported Content here: partnerships.nature.com/commercial-content-at-natu…

All Comments (21)
  • @sunflowerz54
    If they work it will be a miracle for mankind!!! My entire family has died of the dreaded C
  • @fumiyafuse6374
    I wish im still alive if this comes. I have cancer stage 3
  • @djinn4895
    This would be one of the greatest breakthroughs in medicine history!
  • @carlosnino6476
    This is more complicated than show. Every cancer is different, so we have developed vaccines for some cancer, not for others. But this is exciting and everyday we make progress!
  • @gf4453
    Hurray for science! Hurray for scientists!
  • @footfault1941
    Amazing progress at molecular level researches! Commonly shared strategy is to help our own body or immune system to combat. That is, scientists get more, wider & deeper knowledge about organisms including ourselves!
  • @user-xk4vt9ye8j
    I don’t know if this will ever be released. Too much money in keeping you sick.
  • @Eric_Malbos
    Very well illustrated and informative video. There are already some clinics which propose such personnalised treatment for activating dendritic cells. However, the cost is rather high as mentioned. Hopefully, with automation and diffusion this cost will decrease over time.
  • @btsmochimi7924
    Oh I live in a time to see this....what an honor❤😊
  • @pwndpp
    Short and precise video. Loved the overview and animations of methods used for soon-to-be treatments. 🙌🏼
  • @maestoso47
    Scientific journals need to improve their reputation. Continuing to be given funding from companies (like Moderna in this video) really exposes the conflict of interest.
  • Thank you Dr Obaz for your excellent care and compassion. You have gone above and beyond in timely communication and response to our questions and concerns. Thank you for caring and helping us believe in the best possible outcome during our very difficult time…..
  • @jeffmoodie6144
    Glad to see comments from both sides of the arguments.
  • Couldn't the insitu method also trigger auto-immunity? Because radiotherapy will also rupture normal cells and their proteins, exposing them to the activated dendritic cells.
  • @user-wk6bc6hl1i
    Let’s all pray this works and peoples lives can be saved from this terrible disease!
  • @user-bp8yg3ko1r
    This would be a breakthrough! Great video, and very nicely animated as well!
  • There's one thing about this that makes no sense to me: if cancer antigens and neoantigens are already present in the individual's body, why does the immune system not recognise them in the first place? What good does extracting the proteins and reinjecting them do? I feel like this video is missing something out.
  • @miloradvlaovic
    Car T cell vaccines have been aroround fo a while though. Excellent video - informative and easy to follow.