Analysing Protein-Ligand Interactions : Tutorial

Published 2020-09-23
This video explains the basic procedure to analyse the polar and non-polar interactions between a protein ligand complex using PyMOL software.


Protein-Ligand Interactions
Polar Interactions
Non-Polar Interactions
Color coding using PyMOL
Basic Operation of PyMOL

All Comments (21)
  • @hermei8828
    You are saving so much time with these videos! Thank you
  • @arijitdas8569
    I appreciate your informative and simple guide. I request your instructions via a tutorial video on how to dock heavy metal ligands (like Palladium oxide or Silver) to a protein using Autodock 4.2.
  • @keyajoshi3965
    Hello. Thank you for your efforts. Will you be having any idea about analysis of polar interactions through VMD of simulation trajectories?
  • @funny_product
    Sir, is pymol shows the distance of hydrogen bonding in the interaction. Thanks to show the residue
  • @bdilarasu
    OMG thank you so much it helped a lot 👍👍
  • @ashwins5180
    Ur videos are great sir! Its very useful and the explanation was so good. Please make some videos about protocols of protein-ligand interactions and about schrodinger software. Thank you!
  • @haritha9370
    When we require to find the binding site residue, do we have to consider only the residues involved in polar interaction or both polar and non-polar? Pls do reply sir.
  • @shivajidey3152
    Sir it is a wonderful explanation. Can you make a video on protein protein docking using Z dock?
  • Thank you sir for very clear explanation. Can you show us how to remove cofactors that are co-crystallized prior to analysis?