The science of weight loss with Kevin Hall, PhD – Diet Doctor Podcast

Dr sher you are a master of diplomacy and give all of Us lessons in how to listen and engage

The problem with ultra processed foods is the P:E ratio. Real, whole foods contain protein and an energy source (carbohydrate or fat). The majority of ultra processed foods contain little to no protein and both energy sources. In order to meet even your minimum protein requirement for the day eating these foods, you have to over-consume energy.

What a great example how f'ed up nutrition science is. 17 years on the job, never got around to looking at proteins. My compliments for your diplomacy, this must have been tough.

I love the acknowledgment that it's hard to know EVERYTHING the members eat, or that it's hard to restrict them or identify which out of study foods were eaten. David Ludwig has spoken about a study where a store is two Mike's away or so, but what about using those who just cannot get their own foods? We have a variety of prisons and medical facilities that keep people under control for years. Even if they need to agree to the study, there are facilities where foods and activity are monitored quite well. I love the dialog! The concepts feed my mind and perhaps help feed others who have the ability to help fund studies. You are on the right track!

Research Kevin PhD thank you for sharing this knowledge of your experiments and curiosity and consequences and key culprit and understanding . From Johannesburg South Africa 👍

Nice to hear his point of view. Next time he's on could you ask him what he himself actually eats?

Thank you, I thought this was really interesting. I need to watch it a few more times to digest all the info.

Plus inflammation, lectins, oxalates, phytic acid and other phytotoxins. For my N=1 that has been the great difference between keto and carnivore. The possible confounders from the plant content are limitless. Carnivore has been such a brilliant elimination diet (eliminating all the irritants and their effects) it is super-easy to stay on. For me.

Kevin is the man! 🙌 Impressive studies he has done by any standard.

A really interesting interview ty. Brett, am I "The Black Swan"? I wonder if going down the path of ultra processed foods as being a cause is getting side tracked? Over the years as people have had to become 2 income families, and there is no longer a carer in the house preparing food from scratch, these ultra processed foods have become more popular, and it must be hard to find test subjects who are not raised on this model. I'm 58, I think me and my 4 sisters are anomalies. My mother cooked everything from scratch. We were raised on a farm with nearly all beef in our diets, homemade wholemeal bread, home made yoghurt, home cooked beans, lentils, home made jams, pickles and preserves. Home grown eggs, a lot of milk and cheese (it was a dairy farm), lots of fresh fruit, brown rice, brown pasta, no cakes, no biscuits, no cool drink, very little ice cream. I became overweight in my early 30's, and fatty liver (My specialist didn't know what NAFL was back then). I ate a HUGE amount of fruit as a child, to the point my enamel on my teeth was compromised, my other siblings didn't. I wanted to eat more meat, but mum said "no, we don't need it, have another apple". Our mother read the Pritikin diet in 1979, our food became very low in meat, low fat, sugar and salt, and low flavour. My mother very much believed in the pyramid diet plan. I continued to cook from scratch, and still do. My other siblings not so much. I did drink a Coke in my late teens, and then changed to Diet Coke in my 30's. I ate potato chips as a treat maybe once a week, until my 30's and then only as a binge treat rarely, but I continued to eat high fibre, low fat, and got fatter. I've never done a lot of processed foods. And I have heart disease, and pretty normal cholesterol results. Funny enough two of my sisters have gone on to have weight issues, both of them have gone through a few years where they drank Coke. One of them didn't have any weight issues until her 40's when she started to work for Coca-Cola and brought home Coke. BTW, now I'm low carb, high protein, not scared of saturated fats. I still cook everything, and now to avoid seed oils I make my own mayo, and dressings. I have never eaten very much takeout foods. If I want a VERY RARE binge treat on carbs, I pop my own corn and add butter, to avoid the fake butter in commercial popcorn. My husband diabetes is not an issue any more. My parents however have stayed on their high fibre, high carb, low meat diet, and they are both 88 now. Mum has had a triple bypass, and has kidney issues, but not a diabetic as far as she knows, has had weight issues since the 80's, and now arthritis, on statins, and signs of early dementia. Dad has had prostate cancer, macular degeneration, deaf, non hogkins lymphoma, and now has surviced a 3% rare bowel cancer that caused an obstruction an bowel perforation, and now secondaries in his stomach. I guess they are 88, and avoided getting these complications earlier, but they still have them. My instinct is its not ultra processed foods, but something else (fruit, sugar, Coke and other sweet soda drinks). I see the peoples shopping carts all the time, and how its changed over the years. I'm sure it started before ultra processed foods. It did for me.

I look forward to your videos to see if I can learn something new yet after carnivore for a year, and having amazing great results, it’s frustrating watching certain guests that are trying to catch up. Or still skeptical.

Would like to have heard more (or something) about the hormone INSULIN! In the effect on foods!???? Kind of empty information to me? Thanks Bob the welder.

Just love secondary analysis. Data mine and see what you come up with. Love where he is going back and seeing what the effect of the protein content of each individual meal had. As the saying goes GIGO. Glad to know that there's still a lot of good bad science out there. Keep slicing and dicing data, especially with small numbers of subjects and the world is yours. And present it to the mass media and you're a guru

I’m a fairly metabolically broken older person who has tried low carb in the past and it worked but life intervened. I’m starting again now and anticipate it will take at least 3 to 6 months before I see any substantial weight loss although other measures may improve. Short term studies can’t possibly give accurate outcome data and allow for individual differences in genes and clinical history etc. I agree with some comments here that these studies are mostly for obtaining grant monies and ensuring jobs cf what’s happening in a clinical setting at the coalface. I really miss Dr Scher at Diet Doctor and continue to follow him at Metabolic Mind but it narrows the field a bit. Good wishes to anyone on this confusing journey and I think Kevin Hall has just made it more confusing.

Bret, your microphone drops out a few times here. 0:30 is one good example. If you are using a sensitivity setting, you might consider adjusting it. Seems kinda like it's clipping the quietest part?

I wish Dr. Scher would explain to the public that the calorie was only ever a rough approximation of the actual available energy in food. I also wish he would avoid using the term "burn" with regard to the metabolic process that creates energy. I understand they're terms that are convenient, but I firmly believe they are profound misnomers that perpetuate the misconceptions that are deliberately used by big food and big pharma to market their products.

If the press release differs from the study, change the press release.

Thank you for this interesting discussion. Has anyone ever evaluated the effect of the obesogens that are released especially during rapid weight loss like seen in the biggest loser? These obesogens are known to hijack our hormones and slow down our metabolism and it seems reasonable to assume when someone loses weight that quickly that this could have an impact? Thank you!

0:39:00 - take note. Doubly labeled water, wth both oxygen and hydrogen isotopes incorporated into water molecules.

But that makes sense regarding the metabolic slowdown. These people with most weight loss after 6 years have the most amount of slowdown, because they are still depriving the body the most in terms of calorie deficit with a combination of diet and exercise. In the case of more exercise predicting better long term success, since staying in a huge calorie deficit is almost impossible long term, whereas the more you exercise, the more you adapt and enjoy it.