DR. NADIR ALI | Why LDL Goes Up on Low Carb + Is LDL Cholesterol Bad + Risks of Statins

Published 2021-02-10
Dr. Nadir Ali, an interventional cardiologist clears up confusion about LDL and answers questions like is LDL cholesterol really bad for us? Why does LDL cholesterol go up on a low carb diet? Are statins bad for you? Do statins prevent or cause heart disease?

As a leading cardiologist in the high fat, low carb space, Dr. Nadir Ali has been paving the way in advocating that we should not fear high LDL cholesterol when other numbers are in line such as low triglycerides, low insulin and glucose, low inflammation, and high HDL cholesterol.

Statins are commonly prescribed for elevated LDL cholesterol but as Dr. Ali discusses in this video, we may be treating high LDL all wrong. Statins have been shown to have significant side effects like cognitive and memory problems, fatigue, and muscle pain for many patients. Elevated LDL has been shown to be important for sex hormones, muscle function, cognition, and inflammation.

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// D I S C L A I M E R
Dr. Morgan Nolte is a doctor of physical therapy and a board-certified clinical specialist in geriatric physical therapy. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Nolte and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Zivli, LLC and Morgan Nolte, PT, DPT are not liable or responsible for any advice, course of treatment, diagnosis or any conclusions drawn, services or product you obtain through this video or site.

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   • DR. NADIR ALI | Why LDL Goes Up on Lo...  

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All Comments (21)
  • My doctor prescribed the statins, I left them in the cabinet and followed these dietary guideline, my numbers went down, his ego was maintained, and I kept stress levels down by not discussing. I've learned to get my tests done with my doctor, and then not follow his advice. It has worked 100% of the time.
  • I was a patient of Dr. Ali for about 1 yr before I moved away. I’ve never met a doctor that didn’t push drugs or ignore your concerns. He gives his time to educate the public through monthly lectures at the hospital. I wish to God that I could still have access to his practice. I lost 90lbs because of his guidance and improved my health.
  • My wife and I are arguing over LDL. My body, my decision! Trying to stay married, but I have to be alive, to accomplish my goal! My LDL went up, but weight went down, and my sugar is staying below 150, and that’s what my doctor wants! I’ve been Carnivore since August 8, and I’m staying in that lifestyle! If doctors are having trouble finding information on this lifestyle, imagine how much trouble the rest of us are having.
  • @NoName-vx6up
    Finally, a doctor who is willing to question the medical establishment. We need more like this.
  • @samqr169
    This was amazing information, I had high ldl and triglycerides 8 months ago , I took statins and broke into hives all over my body, then I turned to low carb low sugar diet and now my triglycerides have gone down tremendously but LDL is still high . Listening to your conversation gave me such peace of mind . I am really grateful ❤
  • Saying that cholesterol is the problem when the body produces 80-85% of it is a perfect example of association getting conflated with causality.
  • Dr. Ali is essentially seeking to do himself out of a job. How amazingly generous, caring, sacrificial of him --- we need a Nobel Prize category for folks who seek to empower the individual.
  • My experience with LDL and A1C is somewhat unbelievable. I had high total cholesterol (225) and high triglyceride (325) measured after eating good breakfast (I should have not done that) and my A1C was 6.4. My doctor put me on rosuvastatin 20 mg per day (equal to 40 mg of atorvastatin per day). I became quite sick, weak and plenty of muscle pain. My A1C went up to 6.4 from 5.9. I put on 8 pounds. During those days, I used to eat rice (once), bread and some fruits (2-3 types) daily and some meat (on and off) and two eggs. It is quite possible that I am very sensitive to Rosuvastatin. 6 months later, my total cholesterol went down to 120 (LDL was 69), HDL went up by 30% (40), triglyceride was 63 and my A1C dropped to 5.4 (all measured after 14 hour of fasting). I lost 8 pounds. What did I do differently? I reduced rosuvastatin by taking 5 mg every alternate day (that is like 2.5 mg per day) and I stopped eating any added sugar. I eat twice a day now (lunch and dinner and eat absolutely NOTHING in between). I reduced my carb intake by 50%, stopped eating FRUITS completely (fructose in fruits is BAD), increased my protein content (120 gm per day; chicken, two whole eggs, some cheese) and take approximately 4 teaspoon of good oil such as olive oil and avocado oil. I significantly increased vegetables like green stuff (twice a day). I eat a mixture of nuts (walnut, pumpkin seed, flax seed, almonds, peanuts) once a day. I walk 30 minutes everyday, indoor bike for 20 minutes and that is it. I do my best to keep active most of the time (rather than sit for hours etc) by doing household stuff etc. I started avoiding stressful situation as much as possible by not reacting to every little stupid things in life. I have more energy than what I had 20 years ago. I don't get irritated much now. I sleep better. My focus is better. I hardly get tired now. My resting heart rate is very normal now. I am thinking of stopping rosuvastatin once I talk to my doctor next month. I will add resistance training (three times a week) to my routine. And I am a 65 year old person.
  • @user-ux8nr2ej9e
    Yay nerds ! This is very helpful ❤ Just yesterday , after being low carb for two months , I had blood work done . My doctor went nuts . All of my markers were great but my total cholesterol was 300 . He's shure I have familial high cholesterol and am going to drop dead this week . High pressure terror tactics for high intensity statins.. He didn't bat an eye at any of the rest of the data but told me I must take statins because I was " so healthy " and If I wanted to stay that way I needed to take them . It's a wonder we're not all dead from modern medicine . In case you're wondering , I'm not going on the meds . Thank you for saying that a person without familial cholesterol could have a score of 300 on low carb . He got to me enough that I didn't sleep well last night . Thanks to this video I'll sleep better .
  • @dave29339
    I recently had my first physical after doing a low carb / high protein / intermittent fasting diet for a couple years. Within 30 sec of sitting down the Dr. brought up my "very concerning" high cholesterol and how I needed to go on a statin prescription ASAP. I politely declined, but the training was so ingrained that this one number is somehow so devastating to my health... yet literally every other indicator available pointed to me being perfectly fit. I am the perfect example of what Dr. Ali is describing here. I used to have high blood pressure, high triglycerides, high sugar levels, a fatty liver - and now all of that is reversed and I am in the best shape of my life... and my LDL is high.
  • This is a great discussion and sheds some light on my own moderately elevated LDL. I have adopted an OMAD lifestyle for the past 18 months and have attained some shocking goals. However, I’ve changed so many variables that it is unclear which ones have been the major contributors. I suspect, more than anything else, has been the fact that I typically avoid anything from a box, can, or plastic bag that has been highly processed and contains ingredients I can’t pronounce! I do consume a huge amount of food in a 2 hour window in the evening consisting of a Mediterranean style composition (high EVOO, wide range of low lectin vegetables, primarily goat and sheep dairy products, wide range of herbs and spices, and whatever protein my wife feels like having for dinner). I am not a zealot and will consume anything put in front of me when we go out to friends or to a restaurant (which is,I guess, once or twice a week). I had been on meds for diabetes, high cholesterol, and high blood pressure for many years, but shocked my doctor and no longer require any of them. I don’t know how much weight I’ve dropped, but I’ve had to donate all of my clothes and currently maintain a very small wardrobe because it is still dropping. I think OMAD has significant benefits, but suspect avoiding processed foods has contributed more to my improved health. I suspect big Pharma and the Mega food industry has been the main issues in my life. I don’t miss either one. 😀. I am now focusing on gathering data on my fasting insulin and glucose levels to track my HOMA-IR and QUICKI scores along with my triglyceride/HDL ratio and LDL particle sizes. My doctor doubted my efforts when I started this journey, but I now have his full attention (and my own for that matter). He stated at my last visit that if I am able to maintain these results for the long haul that I should write a book! I had to laugh at that and simply responded that there are already hundreds of them written — we just need to get people to read them!😊😊😊
  • @velikijoxotnik
    My weight and health story is very similar to those of others. I'm 5'6", 57 years old. I weighed 155 when I completed my undergrad in 1987. In June 2021, my weight had climbed to 220 lbs, mostly due to working from home due to COVID (less activity and spending too much time a few steps away from the refrigerator). My family doctor told me that I was morbidly obese, and that hit me between the eyes. That day, I decided to change my lifestyle. At first, I was going to do the usual low-fat, calorie-restriction diet. But, I knew that that would ultimately be a failure, long term, because it always is. I did some research and decided to go low-carb (ketogenic). At first, I thought I'd just do it to lose weight then switch to something else, maybe Mediterranean, but then as I learned more, I realized that low-carb is a very sustainable, healthy, life-long dietary option. Along the way, I also incorporated restricted eating (18:6 or 20:4 daily) and periodic multi-day fasts. I absolutely loved the fasts, coupled with low carb and absolutely no sugars or starches. At the beginning of July 2021, I weighed 220. A week before Christmas 2021, I weighed 150... less than my college weight. I had been pre-diabetic, high-blood pressure, high cholesterol. After losing the weight, my A1C is 4.5, my BP is usually 115/70. Great HLD and triglycerides and am Pattern A lipids. But, my LDL is high (not surprisingly), and my doc wants to put me back on a Statin. We're going to have a very long conversation about that, and I doubt VERY seriously that he'll be able to convince me to go back on a statin again. I may even be looking for a new GP, who is knowledgeable of the low-carb lifestyle.
  • @dspirit444
    This Doc is truly AMAZING and I totally get what he's saying, not only can we live w high LDL, it seems LDL plays a major role in our health! Great interview!!
  • @tomasranta6154
    I was a P.T. For 50 years. I saw rhabdomyolosis (acute muscle wasting) frequently and it was always caused by statins. One saving grace for patients is that they usually feel like crap and they quit statins on their own.
  • @gperiaswami3971
    India should feel proud of having produced a doctor of your calibre and honesty!
  • @ttzz175
    I’ve been doing low carb, sometimes ketosis for 8 months. My A1C went from 7.1 to 4.9. HDL 55 TRIG 83 but LDL went up 230. Must be healing! Prior my TRIG were 200s and HDL 27! Thank you high fat diet!
  • @ambarkhan4774
    This doctor is a genius ,i am really impressed by his knowledge over cholesterol.
  • @sarah29880
    I am listening to this right before I go to the doctors and him advocating to put me on a statin due to my high fat low carb diet and my LDL being high, a high HDL and very low triglycerides. Wish me luck!
  • I would have liked to have had more reasons to go on a statin in spite of all the negatives discussed. I just stopped statins after over forty years of use and have been on a keto diet for over two years. I was also able to get off BO Rx and lost a good 30#! I am chagrined to learn all this info on nutrition and statins after being a primary care MD since 1981. Retiring just before COVID-19 gave me a lot of time to study nutrition really for the first time!