Is drinking milk a Superpower? Genetic Mutations: Crash Course Biology #37

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Published 2024-04-02
Science fiction is full of superpowered mutants, but in reality, mutations are much more diverse and complex. Sometimes, they can change someone’s entire body, and other times, we don’t notice them at all! In this episode, we’ll unpack what mutations are, how they work (including substitutions and frameshift mutations), and how scientists are learning to control mutations using tools like CRISPR/Cas9 and gene therapy.

Introduction: Mutations Outside the Movies 00:00
What Are Mutations? 1:20
What Determines Mutations' Effects? 3:10
Types of Mutations 4:16
Positive, Negative, or Neutral? 7:43
Gene Therapy & CRISPR 8:23
Pharmacogenomics 10:59
Review & Credits 11:58

This series was produced in collaboration with HHMI BioInteractive, committed to empowering educators and inspiring students with engaging, accessible, and quality classroom resources. Visit BioInteractive.org/CrashCourse for more information.

Check out our Biology playlist here:    • Biology  

Watch this series in Spanish on our Crash Course en Español channel here:    • Crash Course Biología  

Sources: docs.google.com/document/d/1GLDtAXE6ekg4Chk2qN3TYb…

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All Comments (21)
  • I haven’t been here in a while so I’ve only ever seen Hank Green (I think that’s his name?) do these but oh my gosh this guy is gold
  • My kids and I watch only these biology videos. You’re such an amazing teacher and one of the more engaging ones for sure.
  • @AlienBemular
    There's a character named Bone from One punch man who gets Durability from drinking a lot of milk.
  • @mickmash13
    I have hypermobile EDS, which is a mutation in how my body produces connective tissue. But there are other types that can affect other systems in the body. There's even a lot of variation in how severe hEDS is. I'd be curious to see the genetic variations between various types of EDS and the severity of EDS symptoms.
  • @angiepen
    Yet another example of how awesome Dr. Sammy is. Hopefully he's already set up to do a Crash Course Entomology some time in the near future. :)
  • Dr. Sammy calling for his super suit remind me a Freezone from "The Incredibles." 😊😅😂
  • @johnm3066
    Crazy how our bodies cells and genes resemble a computer program, i.e data structure or algorithm.
  • we also have a gene named sonic hedgehog which is an essential part of embryonic development.
  • @asiaeve4066
    So interesting! Makes me miss biology lol I may take a college class in it senior year 😋🧬✨
  • @abramisme
    nice! thank you for all you do! keep it up!
  • @b1laxson
    It is important to know your family medical history like parent and grand parents. The "mutations" they had are more likely to be ones you have. Knowing what they had to avoid or benefit from is good for yourself. For example there are some at risk of addiction affects so should just never start.
  • Amazing !! Can you make a video explaing the MTHFR gene mutation please ? I carry 2 coppies and it has caused me a lot of problems over my life. Thank you for all your work !! ❤
  • @kmcsciguy
    Excellent video covering mutations and the details!
  • @Caterfree10
    The reason I remember the ACTG letters is bc of GCAT in Homestuck lol. Useless info for me given I’m not exactly a geneticist but hey, it’s a good memory device anyway.