Harvard Professor REVEALS How To SLOW & REVERSE AGING | Dr. David Sinclair

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Published 2019-09-19
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Harvard professor David Sinclair believes that not only can we slow aging down, we can actually reverse it. On this episode of Health Theory with Tom Bilyeu, David Sinclair explains the three levels of aging, and what can be done on each level. He describes the lifestyle changes that slow aging down, the drug treatments that begin to stop aging, and experimental new procedures that may actually reverse aging once they are fully developed.

SHOW NOTES:

David explains the information theory of aging [0:59]
David explains the difference between genes and the epigenome [2:17]
David describes the way that cell stress causes aging [5:20]
David explains what proteins are and how they work [6:40]
David recommends lifestyle changes to slow down or reverse aging [9:14]
David recommends stressing the system by consistent fasting [10:52]
David explains why we don’t live as long as whales [15:01]
David describes resetting the biological clock [16:16]
David explains how to tell when someone is going to die [18:47]
David explains why people are taking metformin [20:03]
David shares his regimen of exercise and metformin [24:18]
David advocates cold exposure [25:28]
David explains work he’s done to try to reset the aging clock [29:01]
David explains why you don’t want to turn the cellular clock back too far [31:37]
David describes the actual process of reversing aging in masses of cells [33:20]
David talks about some results with mice that appear to reverse aging [36:40]
David shares his father’s story of metformin and NMN use [38:10]
David explains the effects of resveratrol [39:07]
David describes the kinds of testing he advocates [43:13]
David shares the impact he wants to have on the world [45:44]

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WEBSITE: www.lifespanbook.com
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FACEBOOK: bit.ly/2mcAPiq

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All Comments (21)
  • @olefella7561
    Eat healthy, do exercise, take vitamin tabs and sleep well. That's what I've done and it's my 90th birthday next week. 😊
  • @ladydee3795
    Short summary: 1. Intermitent fasting - basically being hungry some periods of time - maybe the most important factor! 2. HIIT - high intensity interval training, shocking organism with high pulse rates 3. Low carb diet - no sugar 4. NMN - Nicotinamide mononucleotide 5. Metformin - keeping the blood sugar levels steady by controlling the insuline levels - BUT taking it only on days you are not exercising 6. Exercising - combination of weight lifting, cardio and stretching 7. Shocking body with rapid temperature change - for about an hour - sauna, steam room, hot tube, cold shower - cold exposure builds up brown fat that revs up our metabolism and helps us to stay lean 8. Metabolic winter hypothesis - in our lifestyles we are always warm, wearing jackets, we turn up the heat, we never get exposed to cold unless we don't want to - partly responsible for diabetic problems we have. If you are cold at night, you are gonna turn on your brown fat, burn a lot more energy keeping you warm, and keeping you lean. 9. NAD + booster molecule (nicotinamide adenine dinucleotide) - NR (Nicotinamide Riboside) , NMN 10. Resveratrol - as a supplement - 1 gram a day
  • @MarcusFred-wn3iv
    Been watching, listening, and paying attention to all of predictions and forecasts since early Covid. He hasn't disappointed yet 👌
  • My grandfather is 101 and not out .He is a hard core cricket fan and he is still walking inside the house doing his stuffs by his own and the funny part is he stays upstairs. He is a hardworking man who worked as a postman and as a farmer.Long Live now seen 3 generations.
  • @seymorbutts4283
    My great grandma passed at 107. She slept often, always had a beer or glass of red wine at dinner. She ate home cooked meals and survived the great depression by begging for bread on the street with her sisters. She also drank lots of water and occasionally had orange juice. She stayed sharp speaking two languages and listening to classical music. She passed away a week after being in a nursing home. My family took better care of her until they just couldn't. They all wish they hadn't sent her. R.i.p. great grandma.
  • @----RE
    So basically do the following to live YOUNG & HEALTHY. 1. Exercise (at least 1 hour per day, five days a week; weight lifting is essential) 2. Yoga (30 minutes every morning) 3. Eat clean (consume organic – very important) 4. Diet (reduce meat and increase veg) 5. Stay hungry! 6. Cut carbs to a minimum 7. No sugar at all 8. Monday & Thursday fasting (only fruits and fruit juices) 9. Drink at least 3 litres of clean water (1 litre immediately after you are awake) 10. Sleep (8 hours minimum; Recommendation - 9pm - 6am) 11. Take cold shower 12. Reduce artificial heating and expose yourself in cold weather 13. Use sauna and steam room (Listen, if you are a man, better do this only after you become the father of a child because too much exposure to sauna/steam room/Jacuzzi/hot tub reduces your sperm health) 14. Laugh as much as you can 15. Embrace nature and your true self (go for long aimless walks in the bush, beaches etc. to sense the beauty of nature and to recognise that you are a tiny part of the singularity) 16. Do not keep hatred because it will consume you. Forgive and move on. WE LIVE YOUNG; WE LIVE FREE! 💗
  • Longevity really runs in my family and we all have similar habits. Like every uncle, aunt, grandparent etc. are living 90+ years easily on both sides of my family. Everyone exercising multiple times a week. Everyone. We do not eat really any refined sugars, like zero desserts/sodas/creamers/ice cream etc. None of us are obese, obesity will kill you. All of our meals are home cooked, I actually once went an entire year without going to a restaurant once. Also, we all take care of our skin. Even the men use moisturizers and cleansers and creams etc. I think the biggest thing though is that we are all happy. We don't stress, we sleep well, we relax, we laugh, we smile.
  • @Nobody-cj3sw
    My grandfather died at 98, i never saw him making exercise, ate avery type of food and spent most of the day resting in his business. What i can tell is that he had a very relaxed life.
  • @spacecat5517
    Love the ticker marker at the bottom of the screen that shows order of topics. 👍
  • Guaranteed Agestopper: 1. Eliminate Stress 2. No processed food 3. No industrial refined sugar. Only fruit sugar or natural unprocessed cane sugar or honey in moderate dosis 4. Regular meditation 5. Regular sports 6. Connect with nature without electronic devices regularly 7. Keep your inner child alive 8. Laugh a lot and take life not so serious 9. Connect and hug with the most important people Your welcome ;)
  • @mcleanirish
    Just stumbled across this video - this guy is a fantastic interviewer. To the point, and clear! He asks every question you'd want to ask as a viewer and asks it immediately. This video is 45 minutes long and it was a breeze to get through wasting no time as everyone is concise and articulate!
  • @pstubeing
    You have the BEST guests! And you are an excellent interviewer and your obvious knowledge on this topic is impressive. Thanks and keep it up!
  • It’s hard these days , society force us to persue success “money “ this stress everyone to a point of breakdown. I am 26, I’ve realised that money is necessary in the right amount, I am done persuing to be a millionaire, I am doing more camping , hiking , travelling every now and then, meet family more often and buy a farm to grow food
  • 13:20 I trust this guy only because of what he said: "nobody knows what is the perfect diet, all I can tell you is for rodents" "what we discovered... what my colleagues discovered..." he knows the limitations of his research and he gives credit where it is due, which means that if he says something I am happy he believes in it and does not hype it up. Trustworthy!
  • @oshunsigler
    That last question revealed a true Gem! 💎 We honestly don’t have to eat, there’s people that’ve decided to fast for months & are completely healthy. We literally can survive off of water intake & vitamins. I’ll soon have my own plot of land with a greenhouse where I could grow my own healthy fruits & veggies for times when I choose to eat. ✨
  • @kencarey3477
    I have heard many interviews with David. You asked incredibly good questions
  • @forestfox66
    I have unintentionally fasted daily my whole life 18:6 as my body does not like breakfast, I eat when I am only hungry and stop when I am full, I eat healthily, I sleep in a cold bedroom, I hike mountains every day even in winter, and it makes me feel great, and I live in cold Norway. I have also lived 5 years in the tropics. My body can easily adapt to extreme cold and heat, and I am never sick. At 50 kgs, I am lean and mean. I am 40, look 30 and have a 20-year-old figure. All this new science is very interesting, but listening to your body and what instinctively makes you feel good is equally informative! I am a zoologist, we are animals, but sometimes we just think way too much ;-)
  • It’s always a good sign when the anti aging expert looks over 10 years younger than his actual age!
  • As a recently retired nursing professor, this is one of the best interviews I’ve ever seen… Thank you!
  • @yaqeenhuman8487
    I am 46 according to the gregorian calendar. But I have often seen people who dont know me, think I am barely in my twenties. Here's my secret... it's mind over matter. I command the body to stay youthful... literally. I also use gratitude affirmations alongside such as,"thank you for giving me a youthful appearance, a sculpted face, a tight skin, lush hairline, great eye sight, excellent hearing, great bone structure, etc. etc.". I add to that staying childish. I also don't believe in the clock and calendar. I believe that I am one moment old... the now. I keep learning new skills that subconsciously tell my body to stay functional and youthful as there is a lot to be done.