Coronavirus Pandemic Update 69: "NAC" Supplementation and COVID-19 (N-Acetylcysteine)

Published 2020-05-11
COVID-19 Update 69 with Roger Seheult, MD of Medcram.com bit.ly/3Q2AaMm
N-Acetylcysteine (NAC) is an over the counter supplement that has been utilized by clinicians for years to treat acetaminophen (Tylenol) overdose, as a mucolytic, and for other medical problems. There is compelling research that NAC may also reduce the severity of viral infections like influenza, and perhaps reduce the risk of blood clots (thromboembolism) as well. Could NAC be effective in COVID-19? Dr. Seheult illustrates these ideas and discusses the peer-reviewed data involved.

Links referenced in this video:

Johns Hopkins Tracker - coronavirus.jhu.edu/map.html

www.worldometers.info/coronavirus/

Taylor & Francis - www.tandfonline.com/doi/pdf/10.1080/10715762.2018.…

European Respiratory Journal - www.ncbi.nlm.nih.gov/pubmed/9230243

Biochemical Pharmacology - www.ncbi.nlm.nih.gov/pubmed/19732754

Free Radical Research - www.ncbi.nlm.nih.gov/pubmed/29742938

Experimental and Therapeutic Medicine - www.ncbi.nlm.nih.gov/pmc/articles/PMC5590037/

Medicine - journals.lww.com/md-journal/FullText/2018/11090/N_…

Journal of Medical Toxicology - www.ncbi.nlm.nih.gov/pubmed/22733602

Blood Coagulation & Fibrinolysis - journals.lww.com/bloodcoagulation/Abstract/2006/01…

Redox Biology - www.ncbi.nlm.nih.gov/pmc/articles/PMC5619994/

Circulation - www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117…

Blood Advances - ashpublications.org/bloodadvances/article/4/2/312/…

Journal of Clinical Investigation 1 - www.ncbi.nlm.nih.gov/pubmed/21266777

Journal of Clinical Investigation 2 - www.jci.org/articles/view/41062/figure/2

CEBM - www.cebm.net/covid-19/n-acetylcysteine-a-rapid-rev…

Clinical Trials - clinicaltrials.gov/ct2/show/NCT04374461

www.ncbi.nlm.nih.gov/pmc/articles/PMC2999661/

Some previous videos from this series (visit MedCram.com for the full series):
- Coronavirus Pandemic Update 68: Kawasaki Disease; Minority Groups & COVID-19:    • Coronavirus Pandemic Update 68: Kawas...  
- Coronavirus Pandemic Update 67: COVID-19 Blood Clots - Race, Blood Types, & Von Willebrand Factor    • Coronavirus Pandemic Update 67: COVID...  
- Coronavirus Pandemic Update 66: ACE-Inhibitors and ARBs - Hypertension Medications with COVID-19    • Coronavirus Pandemic Update 66: ACE-I...  
- Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors)    • Coronavirus Pandemic Update 65: COVID...  
- Coronavirus Pandemic Update 64: Remdesivir COVID-19 Treatment Update    • Coronavirus Pandemic Update 64: Remde...  
- Coronavirus Pandemic Update 63: Is COVID-19 a Disease of the Endothelium (Blood Vessels and Clots)?    • Coronavirus Pandemic Update 63: Is CO...  
- Coronavirus Pandemic Update 62: Treatment with Famotidine (Pepcid)?    • Coronavirus Pandemic Update 62: Treat...  
- Coronavirus Pandemic Update 61: Blood Clots & Strokes in COVID-19; ACE-2 Receptor; Oxidative Stress    • Coronavirus Pandemic Update 61: Blood...  
- Coronavirus Pandemic Update 60: Hydroxychloroquine Update; NYC Data; How Widespread is COVID-19? This video was removed by YouTube
- Coronavirus Pandemic Update 59: Dr. Seheult's Daily Regimen (Vitamin D, C, Zinc, Quercetin, NAC)    • Coronavirus Update 59: Dr. Roger Sehe...  
- Coronavirus Pandemic Update 58: Testing; Causes of Hypoxemia in COVID 19 (V/Q vs Shunt vs Diffusion)    • Coronavirus Pandemic Update 58: Testi...  
- Coronavirus Pandemic Update 57: Remdesivir Treatment Update and Can Far-UVC Disinfect Public Spaces?    • Coronavirus Pandemic Update 57: Remde...  
- Coronavirus Pandemic Update 56: What is “Forest Bathing” & Can It Boost Immunity Against Viruses?    • Coronavirus Pandemic Update 56: What ...  
- Coronavirus Outbreak / Pandemic Update 55: How COVID 19 Infection Attacks The Immune System & Differs From HIV:    • Coronavirus Pandemic Update 55: How C...  
- How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment:    • How Coronavirus Kills: Acute Respirat...  

All coronavirus updates are at MedCram.com, and we offer many other medical topics (ECG Interpretation, strokes, thrombosis, pulmonary embolism, myocardial infarction, hypercoagulation, hypertension, anticoagulation, DKA, acute kidney injury, influenza, measles, mechanical ventilation, etc.).

Speaker: Roger Seheult, MD
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.

MedCram provides videos to a variety of medical schools, education programs, and institutions (please contact us at [email protected] if you are interested)

Media Contact: [email protected]
Media contact info: bit.ly/3K4xABM

MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor.
#COVID19 #SARSCoV2 #Coronavirus

All Comments (21)
  • @Medcram
    You can help support our frequent COVID-19 updates by subscribing to this channel and visiting us at www.medcram.com/ for clear and concise explanations of over 60 medical topics. We also offer CMEs for medical professionals, and group rates for medical programs and institutions. All links referenced in this video are in the video description. Quick links to our previous updates on the coronavirus pandemic: - Coronavirus Pandemic Update 68: Kawasaki Disease; Minority Groups & COVID-19: https://youtu.be/Ja-jhcXMGj0 - Coronavirus Pandemic Update 67: COVID-19 Blood Clots - Race, Blood Types, & Von Willebrand Factor: https://youtu.be/JOlVkES_kC8 - Coronavirus Pandemic Update 66: ACE-Inhibitors and ARBs - Hypertension Medications with COVID-19: https://youtu.be/OudhmwulJHY - Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors): https://youtu.be/gzx8LH4Fjic - Coronavirus Pandemic Update 64: Remdesivir COVID-19 Treatment Update: https://youtu.be/Z2hfGcTokiY - Coronavirus Pandemic Update 63: Is COVID-19 a Disease of the Endothelium (Blood Vessels and Clots)? https://youtu.be/Aj2vB_VITXQ - Coronavirus Pandemic Update 62: Treatment with Famotidine (Pepcid)? https://youtu.be/DtPwfihjyrY - Coronavirus Pandemic Update 61: Blood Clots & Strokes in COVID-19; ACE-2 Receptor; Oxidative Stress: https://youtu.be/22Bn8jsGI54 - Coronavirus Pandemic Update 60: Hydroxychloroquine Update; NYC Data; How Widespread is COVID-19? https://youtu.be/fn2yk5SbGiw - Coronavirus Pandemic Update 59: Dr. Seheult's Daily Regimen (Vitamin D, C, Zinc, Quercetin, NAC): https://youtu.be/NM2A2xNLWR4 - Coronavirus Pandemic Update 58: Testing; Causes of Hypoxemia in COVID-19 (V/Q vs Shunt vs Diffusion): https://youtu.be/nO4xgcIaPeA - Coronavirus Pandemic Update 57: Remdesivir Treatment Update and Can Far-UVC Disinfect Public Spaces? https://youtu.be/2U4DAQ3kjRs - Coronavirus Pandemic Update 56: What is “Forest Bathing” & Can It Boost Immunity Against Viruses? https://youtu.be/PgDjVEpEOdQ - Coronavirus Pandemic Update 55: How COVID-19 Infection Attacks The Immune System & Differs From HIV: https://youtu.be/8NffZAGELGg - Coronavirus Pandemic Update 54: COVID-19 Antibody vs. PCR Testing; When to Relax Social Distancing? https://youtu.be/kgzFAdYwYLM - Coronavirus Pandemic Update 53: Anticoagulation; Can Mechanical Ventilation Make COVID 19 Worse? https://youtu.be/o8aG63yigjA - Coronavirus Pandemic Update 52: Ivermectin Treatment; Does COVID-19 Attack Hemoglobin?: https://youtu.be/qc6VV7ue4cE - Coronavirus Pandemic Update 51: State by State Projections; Ultrasound to Diagnose COVID19 Pneumonia: https://youtu.be/E7MufS6dnJw - Coronavirus Pandemic Update 50: Dip in Daily New Deaths; Research on Natural Killer Cells & COVID-19: https://youtu.be/fya6Zwxch88 - Coronavirus Pandemic Update 49: New Data on COVID-19 vs Other Viral Infections (Ventilator Outcomes): https://youtu.be/uaIzj3s3p4A - Coronavirus Pandemic Update 48: Curve Flattening in California, PPE in the ICU, Medication Trials: https://youtu.be/JN-8bGB1cLM - Coronavirus Pandemic Update 47: Searching for Immunity Boosters & Possible Lessons From Spanish Flu: https://youtu.be/H1LHgyfPPQ8 - Coronavirus Pandemic Update 46: Can Hot/Cold Therapy Boost Immunity? More on Hydroxychloroquine: https://youtu.be/EFRwnhfWXxo - Coronavirus Pandemic Update 45: Sharing Ventilators, More on Sleep, Immunity, & COVID-19 Prevention: https://youtu.be/G1zsE9_85i4 - Coronavirus Pandemic Update 44: Loss of Smell & Conjunctivitis in COVID-19, Is Fever Helpful? https://youtu.be/A4eu-h_owaI - Coronavirus Pandemic Update 43: Shortages, Immunity, & Can a TB Vaccine (BCG) Help Prevent COVID-19? https://youtu.be/LqKwAIIy-Mo - Coronavirus Pandemic Update 42: Immunity to COVID-19 and is Reinfection Possible? https://youtu.be/q4P91VrfPGw - Coronavirus Pandemic Update 41: Shelter In Place, FDA Investigates Hydroxychloroquine for COVID-19: https://youtu.be/hPz5KxgI_K4 - Coronavirus Pandemic Update 40: Ibuprofen and COVID-19 (are NSAIDs safe?), trials of HIV medications: https://youtu.be/dT6mHi_8V5E - Coronavirus Pandemic Update 39: Rapid COVID-19 Spread with Mild or No Symptoms, More on Treatment: https://youtu.be/AToF8O5T86s - Coronavirus Pandemic Update 38: How Hospitals & Clinics Can Prepare for COVID-19, Global Cases Surge: https://youtu.be/MoisrCTu0SY - Coronavirus Pandemic Update 37: The ACE-2 Receptor - The Doorway to COVID-19 (ACE Inhibitors & ARBs): https://youtu.be/1vZDVbqRhyM - Coronavirus Pandemic Update 36: Flatten The COVID-19 Curve, Social Distancing, Hospital Capacities: https://youtu.be/vww1nIIoqmw - Coronavirus Pandemic Update 35: New Outbreaks & Travel Restrictions, Possible COVID-19 Treatments: https://youtu.be/vE4_LsftNKM - Coronavirus Epidemic Update 34: US Cases Surge, Chloroquine & Zinc Treatment Combo, Italy Lockdown: https://youtu.be/U7F1cnWup9M - Coronavirus Epidemic Update 33: COVID-19 Medication Treatment Trials, Global Testing Remains Limited: https://youtu.be/Mm7UrZeu-74 - Coronavirus Epidemic Update 32: Important Data from South Korea, Can Zinc Help Prevent COVID-19? https://youtu.be/Eeh054-Hx1U - Coronavirus Epidemic Update 31: Mortality Rate, Cleaning Products, A More/Less Severe Virus Strain? https://youtu.be/7YI2tOoVVpk - Coronavirus Epidemic Update 30: More Global COVID-19 Outbreaks, Vitamin D May Aid Prevention: https://youtu.be/gmqgGwT6bw0 - Coronavirus Epidemic Update 29: Testing problems, mutations, COVID-19 in Washington & Iran: https://youtu.be/XjEacUyp4vY - Coronavirus Epidemic Update 28: Practical Prevention Strategies, Patient Age vs. Case Fatality Rate: https://youtu.be/quDYb_x54DM - Coronavirus Epidemic Update 27: Testing accuracy for COVID-19 (CT Scan vs. RT-PCR), California Cases: https://youtu.be/xQwfuJgJ9lo - Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic? https://youtu.be/bV1CZxJ-uvU - Coronavirus Epidemic Update 25: Vaccine Developments, Italy's Response, and Mortality Rate Trends: https://youtu.be/UImSVhLLeGY - Coronavirus Epidemic Update 24: Infections in Italy, Transmissibility, COVID-19 Symptoms: https://youtu.be/wFoj2L2LpNA - Coronavirus Epidemic Update 23: Infections in Kids & Pregnancy, South Korea, Spillover From Bats: https://youtu.be/JGhwAGiAnJo - Coronavirus Epidemic Update 22: Spread Without Symptoms, Cruise Quarantine, Asymptomatic Testing: https://youtu.be/OqpHvK0XADY - Coronavirus Epidemic Update 21: Antibodies, Case Fatality, Clinical Recommendations, 2nd Infections?: https://youtu.be/9BYaywITXYk - Coronavirus Epidemic Update 20: Misinformation Spread, Infection Severity, Cruise Ship, Origins: https://youtu.be/Ka48UZDDzLY - Coronavirus Epidemic Update 19: Treatment and Medication Clinical Trials: https://youtu.be/4HK9QEy1KJ8 - Coronavirus Epidemic Update 18: Cellphone Tracking, Increase in Hospitalizations, More Sleep Tips: https://youtu.be/vE4pBkslqS4 - Coronavirus Epidemic Update 17: Spike in Confirmed Cases, Fighting Infections with Sleep (COVID-19): https://youtu.be/wlbM6VVkVZM - Coronavirus Epidemic Update 16: Strengthening Your Immune Response to Viral Infections (COVID-19): https://youtu.be/qqZYEgREuZ8 - Coronavirus Epidemic Update 15: Underreporting, Prevention, 24 Day Incubation? (COVID19): https://youtu.be/o804wu5h_ms - Coronavirus Epidemic Update 14: Hospital spread of infection, WHO allowed in China, N-95 masks: https://youtu.be/pDnmHu8x9C4 - Coronavirus Epidemic Update 13: Li Wenliang, nCoV vs Influenza, Dip in Daily Cases, Spread to Canada: https://youtu.be/0UgrPgJdzp0 - Coronavirus Epidemic Update 12: Unsupported Theories, Pneumonia, ACE2 & nCoV: https://youtu.be/GT3_A1bf9pU - Coronavirus Epidemic Update 11: Antiviral Drugs, Treatment Trials for nCoV (Remdesivir, Chloroquine): https://youtu.be/pfGpdFNHoqQ - Coronavirus Epidemic Update 10: New Studies, Transmission, Spread from Wuhan, Prevention (2019-nCoV): https://youtu.be/gPwfiQgGsFo - Coronavirus Epidemic Update 9: Fecal-Oral Transmission, Recovery vs Death Rate: https://youtu.be/8Hjy3UfaTSc - Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine, & MRSA: https://youtu.be/GpbUoLvpdCo - Coronavirus Epidemic Update 7: Global Health Emergency Declared, Viral Shedding: https://youtu.be/nW3xqcGidpQ - Coronavirus Outbreak Update 6: Asymptomatic Transmission & Incubation Period: https://youtu.be/UGxgNebx1pg - Coronavirus Update 5: Mortality Rate vs SARS / Influenza: https://youtu.be/MN9-UXsvPBY - How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment: https://youtu.be/okg7uq_HrhQ - Coronavirus Update 3: Spread, Quarantine, Projections, & Vaccine: https://youtu.be/SJBYwUtB83o - Coronavirus Symptoms, Diagnosis, Treatment: https://youtu.be/UCG3xqtcL3c - Coronavirus Outbreak - Transmission & Updates: https://youtu.be/9vMXSkKLg2I
  • @MrGuard1347
    This man needs to be remembered as a hero in our history books
  • @binary964
    mom was discharged from hospital last week, severe covid. her room air o2 sat was only 88% supine, 93% prone, so she's on o2 support 24/7 at home. her doc gave her dextromethorphan cough syrup, didn't help her very productive cough, so she refused to take more of it after the first bottle. switched her to NAC and Symbicort (by advice from my pulmonologist colleague) plus several other supplements, her sat went up to 95% supine with room air in just 3 days.
  • @jennybfoxxy
    Better than any journalist I've ever heard from. He shows his hypothesis, breaks it down from start to finish and then references tons of papers with findings that also explain his hypothesis in detail. I could listen to this forever!! Thank God for science ❤️
  • @Brockt87
    I’ve used NAC for 7 years, it’s awesome. Important note, anyone w chronic issues or lifestyle stresses (lack of sleep drinking smoking taking any medication regularly etc) needs a lot more than the ideal subjects NaC has been successfully tested on.600mg daily worked for them, but anyone w asthma allergies sinus infections fibromyalgia Lyme etc arthritis usually needs at least 1200mg 2-3 times a day, & more usually works better.
  • @rzioni1971
    As a doctor i always give my patients with respiratory illness a combination of antibiotic and NAC. I do it for years. Regardless of covid 19. The reason i do it it simple. I get much better result then if i send them with antibiotic only. So if this work for covid as well its great. Lets hope
  • @SimplyMilli
    They just removed NAC from most stores.. I wonder why? 🤔
  • I’m watching this instead of the news. This gives me hope. Great work, and thanks for charing 👍
  • @kph1955
    I took NAC when I had Hep C and within 2 weeks it brought my liver enzymes back to normal.
  • @jeffhayden2737
    Dr. Quay Atossa therapeutics in Seattle area has been using nebulized NAC and Heparin with good results and has published results , he is now trying to get clinical trial initiated.
  • @agriperma
    I have been taking NAC for years now, and have often mentioned that if I only took one supplement it would be NAC. I became aware of NAC many years ago, when it was prescribed by our pediatrician for our toddlers respiratory problems. the medication was from Germany, it worked very well, and we had been given other medications that did not help previously. I always do research on any medication given to my son, and was amazed at how safe and all the benefits NAC had on the human body. Since I often get bad lung problems when I get a flu, I decided to order a bottle, it is not expensive. NAC not only helped me for any breathing problems, it also had other unexpected benefits, such has helping lower spikes in the audible level of my tinnitus. ( some food and medications seem to aggravate Tinnitus, NAC seems to help lower those spikes ). and finally, cold sores were basically eliminated.
  • @fwhites
    I had what I thought was the flu in February. Unfortunately I waited until it got really bad before I acted but, I drank 1 heaping tablespoon of MSM (organic Sulphur) and 3000 mg of NAC 2 times. The next day I could breathe normally and felt much better. Body aches and fatigue were almost completely gone. My girlfriend and I both did this as she was as sick as I was. After the second day I was back to normal. You are definitely on to something big! Please don't stop....you could save many lives!
  • @DrJimmyGutman
    I have published many books on the topic of glutathione. Wow, I learned a TON from Roger's videos. BRILLIANT!
  • Coincidentally. I have carried NAC and Aspirin on me for some years. Told my wife - if I have a stroke give me the NAC, if a heart attack, the Aspirin and NAC.
  • @teaves8251
    I so enjoyed this video! I have been taking NAC since 2007 in an attempt to keep my lungs clear. I have smoked cigarettes for at least 30 years before quitting and a lover of joints which are high in tar. I have really slowed down on joints now. I have always gotten quick results for clearing my lungs with NAC overnight. I take it at bedtime 600-1200mg. I had pneumonia many years ago and started taking probiotics and upped the dose if I felt tweaked with some bug. I take other Vitamins and extracts to ward off viruses. Oregano extract oil drops and elderberry drinks with vinegar and honey are great anti-virals combined with Vit C and Zinc. I can feel most things try to come on at night so thats when I take my handful of goodies and whatever it was is gone by morning. I love NAC!
  • @Wraith-Kryptos
    ...And that's how Roger Seheult saved millions of lives
  • @billmeyer3436
    I have been taking NAC since the beginning of this outbreak. I happened by it randomly through a video I watched before things got bad in Jersey. I am a hospice chaplain in NJ and have had numerous opportunities for infection, but had a recent negative anti-body test. I am grateful I don't seem to have been infected but I am wondering why, given the exposure I have had. I take a cocktail of NAC, zinc, vitamin D, vitamin C, losartan, and quercetin every day. Wonder if that has mitigated any possible exposure.
  • @marysmith4811
    FYI...You used to be able to find NAC on Amazon. Since ppl started talking about it as a treatment for COVID, they will not allow anyone to sell it. Let THAT sink in. And understand that if Amazon becomes our sole market one day, they will dictate what we are allowed to buy.
  • The most significant effect I noticed when I took NAC was a thinning of lung mucus, making it easier to cough productively.