Coronavirus Pandemic Update 54: COVID-19 Antibody vs. PCR Testing; When to Relax Social Distancing?

Thanks for supporting our COVID-19 video updates by subscribing to this channel, and visiting us at www.medcram.com/ At our website, you can view all of our videos and CLEAR explanations of over 60 medical topics. We also offer CME/CEUs for medical professionals, medical programs, hospitals, and institutions. All links referenced in this video are in the video description. Quick links to our previous updates on the coronavirus pandemic: - Coronavirus Pandemic Update 53: Anticoagulation; Can Mechanical Ventilation Make COVID 19 Worse? https://youtu.be/o8aG63yigjA - Coronavirus Pandemic Update 52: Ivermectin Treatment; Does COVID-19 Attack Hemoglobin?: https://youtu.be/qc6VV7ue4cE - Coronavirus Pandemic Update 51: State by State Projections; Ultrasound to Diagnose COVID19 Pneumonia: https://youtu.be/E7MufS6dnJw - Coronavirus Pandemic Update 50: Dip in Daily New Deaths; Research on Natural Killer Cells & COVID-19: https://youtu.be/fya6Zwxch88 - Coronavirus Pandemic Update 49: New Data on COVID-19 vs Other Viral Infections (Ventilator Outcomes): https://youtu.be/uaIzj3s3p4A - Coronavirus Pandemic Update 48: Curve Flattening in California, PPE in the ICU, Medication Trials: https://youtu.be/JN-8bGB1cLM - Coronavirus Pandemic Update 47: Searching for Immunity Boosters & Possible Lessons From Spanish Flu: https://youtu.be/H1LHgyfPPQ8 - Coronavirus Pandemic Update 46: Can Hot/Cold Therapy Boost Immunity? More on Hydroxychloroquine: https://youtu.be/EFRwnhfWXxo - Coronavirus Pandemic Update 45: Sharing Ventilators, More on Sleep, Immunity, & COVID-19 Prevention: https://youtu.be/G1zsE9_85i4 - Coronavirus Pandemic Update 44: Loss of Smell & Conjunctivitis in COVID-19, Is Fever Helpful? https://youtu.be/A4eu-h_owaI - Coronavirus Pandemic Update 43: Shortages, Immunity, & Can a TB Vaccine (BCG) Help Prevent COVID-19? https://youtu.be/LqKwAIIy-Mo - Coronavirus Pandemic Update 42: Immunity to COVID-19 and is Reinfection Possible? https://youtu.be/q4P91VrfPGw - Coronavirus Pandemic Update 41: Shelter In Place, FDA Investigates Hydroxychloroquine for COVID-19: https://youtu.be/hPz5KxgI_K4 - Coronavirus Pandemic Update 40: Ibuprofen and COVID-19 (are NSAIDs safe?), trials of HIV medications: https://youtu.be/dT6mHi_8V5E - Coronavirus Pandemic Update 39: Rapid COVID-19 Spread with Mild or No Symptoms, More on Treatment: https://youtu.be/AToF8O5T86s - Coronavirus Pandemic Update 38: How Hospitals & Clinics Can Prepare for COVID-19, Global Cases Surge: https://youtu.be/MoisrCTu0SY - Coronavirus Pandemic Update 37: The ACE-2 Receptor - The Doorway to COVID-19 (ACE Inhibitors & ARBs): https://youtu.be/1vZDVbqRhyM - Coronavirus Pandemic Update 36: Flatten The COVID-19 Curve, Social Distancing, Hospital Capacities: https://youtu.be/vww1nIIoqmw - Coronavirus Pandemic Update 35: New Outbreaks & Travel Restrictions, Possible COVID-19 Treatments: https://youtu.be/vE4_LsftNKM - Coronavirus Epidemic Update 34: US Cases Surge, Chloroquine & Zinc Treatment Combo, Italy Lockdown: https://youtu.be/U7F1cnWup9M - Coronavirus Epidemic Update 33: COVID-19 Medication Treatment Trials, Global Testing Remains Limited: https://youtu.be/Mm7UrZeu-74 - Coronavirus Epidemic Update 32: Important Data from South Korea, Can Zinc Help Prevent COVID-19? https://youtu.be/Eeh054-Hx1U - Coronavirus Epidemic Update 31: Mortality Rate, Cleaning Products, A More/Less Severe Virus Strain? https://youtu.be/7YI2tOoVVpk - Coronavirus Epidemic Update 30: More Global COVID-19 Outbreaks, Vitamin D May Aid Prevention: https://youtu.be/gmqgGwT6bw0 - Coronavirus Epidemic Update 29: Testing problems, mutations, COVID-19 in Washington & Iran: https://youtu.be/XjEacUyp4vY - Coronavirus Epidemic Update 28: Practical Prevention Strategies, Patient Age vs. Case Fatality Rate: https://youtu.be/quDYb_x54DM - Coronavirus Epidemic Update 27: Testing accuracy for COVID-19 (CT Scan vs. RT-PCR), California Cases: https://youtu.be/xQwfuJgJ9lo - Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic? https://youtu.be/bV1CZxJ-uvU - Coronavirus Epidemic Update 25: Vaccine Developments, Italy's Response, and Mortality Rate Trends: https://youtu.be/UImSVhLLeGY - Coronavirus Epidemic Update 24: Infections in Italy, Transmissibility, COVID-19 Symptoms: https://youtu.be/wFoj2L2LpNA - Coronavirus Epidemic Update 23: Infections in Kids & Pregnancy, South Korea, Spillover From Bats: https://youtu.be/JGhwAGiAnJo - Coronavirus Epidemic Update 22: Spread Without Symptoms, Cruise Quarantine, Asymptomatic Testing: https://youtu.be/OqpHvK0XADY - Coronavirus Epidemic Update 21: Antibodies, Case Fatality, Clinical Recommendations, 2nd Infections?: https://youtu.be/9BYaywITXYk - Coronavirus Epidemic Update 20: Misinformation Spread, Infection Severity, Cruise Ship, Origins: https://youtu.be/Ka48UZDDzLY - Coronavirus Epidemic Update 19: Treatment and Medication Clinical Trials: https://youtu.be/4HK9QEy1KJ8 - Coronavirus Epidemic Update 18: Cellphone Tracking, Increase in Hospitalizations, More Sleep Tips: https://youtu.be/vE4pBkslqS4 - Coronavirus Epidemic Update 17: Spike in Confirmed Cases, Fighting Infections with Sleep (COVID-19): https://youtu.be/wlbM6VVkVZM - Coronavirus Epidemic Update 16: Strengthening Your Immune Response to Viral Infections (COVID-19): https://youtu.be/qqZYEgREuZ8 - Coronavirus Epidemic Update 15: Underreporting, Prevention, 24 Day Incubation? (COVID19): https://youtu.be/o804wu5h_ms - Coronavirus Epidemic Update 14: Hospital spread of infection, WHO allowed in China, N-95 masks: https://youtu.be/pDnmHu8x9C4 - Coronavirus Epidemic Update 13: Li Wenliang, nCoV vs Influenza, Dip in Daily Cases, Spread to Canada: https://youtu.be/0UgrPgJdzp0 - Coronavirus Epidemic Update 12: Unsupported Theories, Pneumonia, ACE2 & nCoV: https://youtu.be/GT3_A1bf9pU - Coronavirus Epidemic Update 11: Antiviral Drugs, Treatment Trials for nCoV (Remdesivir, Chloroquine): https://youtu.be/pfGpdFNHoqQ - Coronavirus Epidemic Update 10: New Studies, Transmission, Spread from Wuhan, Prevention (2019-nCoV): https://youtu.be/gPwfiQgGsFo - Coronavirus Epidemic Update 9: Fecal-Oral Transmission, Recovery vs Death Rate: https://youtu.be/8Hjy3UfaTSc - Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine, & MRSA: https://youtu.be/GpbUoLvpdCo - Coronavirus Epidemic Update 7: Global Health Emergency Declared, Viral Shedding: https://youtu.be/nW3xqcGidpQ - Coronavirus Outbreak Update 6: Asymptomatic Transmission & Incubation Period: https://youtu.be/UGxgNebx1pg - Coronavirus Update 5: Mortality Rate vs SARS / Influenza: https://youtu.be/MN9-UXsvPBY - How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment: https://youtu.be/okg7uq_HrhQ - Coronavirus Update 3: Spread, Quarantine, Projections, & Vaccine: https://youtu.be/SJBYwUtB83o - Coronavirus Symptoms, Diagnosis, Treatment: https://youtu.be/UCG3xqtcL3c - Coronavirus Outbreak - Transmission & Updates: https://youtu.be/9vMXSkKLg2I

I'd much rather watch one of these than all the network news combined. I've been watching since Pandemic Update #1 and wouldn't miss one. I've watched #35 7 times now, following all the links. I just wish the people that we've put in charge would take the time to watch them also. Clear & concise, as it should be. Thank you so much for what you're doing.

I recently retired from a 30-year career in computer science, networking, and software development. But if I had seen videos like this back in the late '80s when I was an undergrad, there's a damn good chance I would have abandoned that entirely, and switched to a Medical educational track. FASCINATING, USEFUL, AND FANTASTIC MATERIAL, ROGER! KEEP UP THE GOOD WORK! I have zero doubt you're influencing numerous young people to pursue a Med/STEM career.

Everyone should start watching this channel instead of the lame news channels that give nothing but fear and anxiety. This channel is so comforting in the gloomy days

I just want to say how much I appreciate the hard work you do to disseminate this knowledge to us. You have a very pleasant voice and a keen sense of articulation both verbally and thought process-wise. Thank you Dr. Seheult!

You give out more info in 17-20 minutes that the networks do in a week.Keep it up.

When a woman helps you catch 200 pill-bugs, you just KNOW she's a keeper!

These are excellent. They also help with the unknowns in turn helps people cope with education and knowledge, thus leads to less anxiety.

Thanks so much Dr. Seheult for these daily updates! As a scientist (immunologist, PhD student) is nice to hear proper scientific explanations behind the latest updates and discussing the latest clinical evidence, calmly and rationally! Just some thoughts: it would have been nice to clarify the difference (and mathematical definition) between diagnostic test sensitivity (probability of true positive detection; the higher the percent sensitivity the lower the number of false negatives) and specificity (probability of true negatives detection; the higher the percentage specificity the lower the number of false positives). It's important to make the distinction, since, for example, a lot of the serological tests out there have ~90-93% sensitivity (a bit worse than nucleic acid testing but not far) but near 100% specificity. This means that these tests, even though only ~90-03% efficient at detecting true positive antibodies in those previously exposed and recovered from CoVID-19, are still very good at detecting true negatives (many are near 100%): Worse case scenario, even if the test comes out with a false negative (and the person has developed immunity due to previous exposure), and that person can't return to normal life (i.e. intensivist returning to the ICU), no biggie, that will only happen ~93% of the time. However, at least there's a very low chance that a person will test false positive (i.e. test falsely indicates immunity against the virus when in fact the person has not developed antibodies against SARS-CoV2) and goes out to be exposed due to erroneous testing results. Here's a list of FDA approved serology test kits in the US and kits approved outside of the US for reference if you're interested (Johns Hopkins Center for Health Security: https://www.centerforhealthsecurity.org/resources/COVID-19/serology/Serology-based-tests-for-COVID-19.html) Also, while it's true that as of 4/14/20 there are no at-home test kits available, there's quick progress being made. Scanwell Health (develop at-home test kits for UTIs, pregnancy test kits, etc.) and Lemonaid (telehealth company) are the closest companies to getting FDA's EUA for an at-home test kit. The kit was used in China (not as at-home but administered in clinics) around Wuhan in the hardest-hit regions where there were severe nucleic acid test kit shortages. Here are the sources: https://www.cleveland.com/news/2020/04/at-home-testing-for-coronavirus-slowed-by-fda-rules-health-matters.html https://time.com/5809753/at-home-coronavirus-test/ Interestingly, North Carolina's state legislature approved a $100,000 study at Wake Forest Baptist Health for 1,000 at-home test kits from Scanwell to monitor a group of selected study subjects each month (NC senator hopeful the data can be used to determine quarantine measures in the state). Here's the source: https://abc11.com/coronavirus-antibody-test-nc-covid-19/6100410/ Also, BD & Biomedomics have gotten approval for a point-of-care 30-min capillary or venous blood serological tets kit in the USA that's already currently in use along with a few others (this one seems to be the most compact and quickest test kit that I've seen in use so far) https://www.biomedomics.com/products/infectious-disease/covid-19-rt/ So, it seems that there's more serious thought and effort (at the federal level from biotech companies capital investment) being put towards serological testing. Hopefully the data will at least allow epidemiologists and immunologist/microbiologist researchers have a better understanding of the prevalence of the disease after all the data comes through by the end of this whole pandemic. Although, I honestly remain somewhat skeptic about the reliability of the data from serological testing in informing authorities about quarantine measures.

Once again thank you for all that you do for us and for saving lives. 💖Stay safe💖

Thank you for helping us through this difficult time. These videos are essential viewing for me. So clear.

Thank you for that. I will inform my family that they need help also.

Thank you for finding time in making these videos, they really help a lot. God bless!

Clarity thank you so much - greetings from UK.

Thank you again! 🙏Stay safe!❤️

Thanks Dr. Long for the day where you don't have to do this anymore. Your very appreciated.

I have been watching the Korean news and they are seeing numbers of patient that have been treated already for the virus and are coming back to hospital with symptoms and testing positive again. some are speculating that it might be "reactivation" rather than reinfection. This worries me as the people that have recovered from the virus may be out in the public and can act as asymptomatic carriers again.

Thank you Dr. Seheult! You can explain these processes so clearly, it is easy to follow, luckily I have a masters degree in biology so I understand a lot, but nevertheless thumbs up for clarity!

Thank you so much for this Doc!

Thanks for all the work you put in to these videos.