The Brothers Who Suffer From Paralysis When The Sun Goes Down | Our Life

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That disrespectful reporter saying "I've been waiting for a story like this my whole life" & then laughs makes me absolutely disgusted!!! These are human beings, young boys, with a debilitating condition not just some "story" or anything to laugh about.

The dad massaging their face because they said their teeth hurt when this happens. This has to be some of the purest love. Honestly so beautiful.

I’m so glad they found a treatment for the boys. I only wish they could have treated them much sooner. To have to live with that horrible condition for 13 years first. Thank you to the reporter that got their story recognized and to the physicians who figured it out and treated them. And all the thanks goes to their loving father and family that took care of them and never gave up.

The disease these boys are suffering from could be what is known as ‘Hypokalemic night time muscle paralysis” which is a rare genetic disease involving the calcium channel system in skeletal muscle cells which often can also cause intermittent low potassium and thus called hypokalemic muscle paralysis. Autosomal dominant from a mutation on Chromosome 1 mostly affecting males. And as here this disease affects the Asian population more. Interesting already two younger brothers have passed at a very young age implying that these sons were probably homozygous. And as most AD genetic diseases homozygous is lethal often in early years. These two boys who are older and suffering are probably heterozygous. And this have been able to survive longer. On the premise of the video-Interesting that they are called “solar”. This may be a hindrance to searching out the cause. The sun(light) and night(dark) may have something to do with this condition. Or perhaps nothing at all. However, is it the activity of being active that depletes the dopamine according to these doctors diagnosis— which is secreted from the ‘Substantia nigra’ in the brain (which should show changes on CT scan of the brain). So if the boys slept during the day and were rigid , would they be relaxed during the night? If so then they would NOT be solar boys. However if they are still relaxed during sleeping during the day and rigid at night despite being fully awake, then yes they are solar boys. There might be a problem with melatonin and it’s interaction with Dopamine ie the substance that seems to get depleted. It would be worth doing sleep studies on these boys. Lastly, the body has away of destroying dopamine including dopamine like drugs and over time they will need more and more dopamine. And perhaps at one point dopamine will not work. Dopamine is used for many other neuro muscular diseases like Parkinson’s disease. And bcs the body destroys dopamine, the dose will have to be increased over times. These two young boys are young and one cannot just keep giving dopamine without an actual diagnosis. (We Can in Parkinson’s disease Bcs PD generally -not always affects older people. So in these two young boys cases, it is prudent to discover the genetic bio chemical problem for this disease. Obviously most likely inherited, a recessive trait?? “Y” linked or one thst skips a generation. A detailed history from the father and his family of origin as well as the mother’s would also be VERY helpful. Two other disease to think about round be KLS (sleeping beauty disease although more common if adolescent females it can affect males) or a variant of porphyria of which there are many. By the speed of the investigations done at these centers I do not think these diseases were excluded as specialized tests take a lot longer.

When the dad says "look at the elephant, his eyes are so beautiful", i can say that he has a pure heart and a good soul.

This made me cry, not just because how terrifying this disease is but because of the purity of this dad. He is such a loving and care parent, you can see his love through his eyes.

Boys, your father is EVERYTHING!!! Honor him always! His love is beyond compare!

the look of relief on the fathers face is absolutely priceless. His stress levels were so deeply etched in his being that as soon as they started to move the smile....you could see the world lifted from his shoulders.

The dad is SO caring, even for dads standards, give him a father of the year award!

Now this is a real father, love's his children unconditionally and does everything he can for his sick son's and his family. We need more men like him in the world. ❤️❤️❤️

Just to say - from a cultural perspective - the mother may be just as caring and loving, but isn’t able to or doesn’t want to be shown on camera.

There was an American family that had two small children with a similar condition. They were featured on Mystery Diagnosis. I believe it was a neurologist who gave them L-Dopa, and they now live normal lives. Whether it's the same condition or not, it presented in an almost identical fashion. I'm glad this family got the help they needed.

Kudos to the cleric for admitting he has no idea what the sickness was There's so many false clerics who would have taken advantage of that poor family

We always brag about a mother's love but after seeing this father.. He deserves the same accolades.. Best Dad!! GOD bless him. 🙏🏾

What a miraculous story. The dad was so loving and caring all throughout this scary journey.

1. What a great father, family really. 2. Thank goodness for the news crew and the doctors' support. 3. I never knew that dopamine played so many diverse roles in the body.

These boys are blessed with a father who doesn't need sleep. What an inspiration and example of what a father can be!

The look in dad's eyes that first night walking out of the hospital with his sons walking too just got me crying. The relief and astonishment in his eyes mixed with gratitude I think every parent who truly loves their children knows that look. My heart swelled when those smiles showed up after the dopamine in pill form was first given. What a thrill to see the nightlife for the first time for them...or eat at night. I read from a medical source that it was partly due to the parents being cousins...that whole reason why it shouldn't be done between cousins unless they are like 4th or 5th cousins. IF that was the reason, they were lucky; many issues stemming from cousins marrying are far worse and not treatable. I wonder if in their future, there is a lesser or greater chance of them getting Parkinson's or any of the issues stemming from that chemical interaction. I laughed so hard when one of the boys was lying on the car hood, the alarm went off, and he looked around and 'oopsed' in gesture! 😄

I’m so happy for these boys, their family and the doctors. The love this father has is beautiful to see.