What Every Woman MUST KNOW to PREVENT Alzheimer’s | Neuroscientist Lisa Mosconi X Rich Roll Podcast

407,977
0
Published 2024-03-11
Rich sits down with neuroscientist Dr. Lisa Mosconi to discuss menopause and brain health, Alzheimer’s and dementia, neuro-nutrition, hormone replacement therapy, and much more. To read more about Dr. Mosconi and peruse the full show notes, go here👉🏾bit.ly/richroll819
✌🏼🌱 - Rich

This Episode Brought To You By...

SQUARESPACE
Get 10% OFF with code RichRoll 👉 bit.ly/squarespace2024

SEED
Use code RICHROLL25 for 25% OFF 👉 bit.ly/seed2024

LISTEN / SUBSCRIBE TO THE PODCAST
Apple Podcasts: bit.ly/rrpitunes
Spotify: bit.ly/rrpspotify
Google: bit.ly/rrpgooglepods

Meal Planner: meals.richroll.com/
Voicing Change Book: richroll.com/vc
Clips Channel: youtube.com/c/RichRollPodcastClips
Newsletter: bit.ly/rollcallemail

CONNECT WITH RICH
✩ Website - richroll.com/
✩ Rich Roll Podcast - richroll.com/all-episodes/
✩ Instagram - www.instagram.com/richroll/
✩ Twitter - twitter.com/richroll
✩ Facebook - www.facebook.com/richrollfans
✩ Strava - www.strava.com/athletes/14443?oq=rich
✩ Memoir: Finding Ultra - www.richroll.com/shop/books/finding-ultra/
✩ Meals - meals.richroll.com/
✩ Cook - The Plantpower Way - www.richroll.com/shop/books/the-plantpower-way-sig…
✩ Italian! - The Plantpower Way: Italia - www.richroll.com/shop/books/the-plantpower-way-ita…
✩ Support - www.patreon.com/richroll

FILMED AND EDITED BY BLAKE CURTIS, DAN DRAKE AND MORGAN MCRAE
www.blakecurtis.net/
www.dandrake333.com/

TIMESTAMPS
00:00:00 Intro
00:01:15 Dr. Mosconi's Background
00:03:34 Interest in Neuroscience
00:04:37 Move to the United States
00:06:14 Gender Disparities in Alzheimer's
00:08:27 Historical Context of Women's Health in Science
00:15:16 Bikini Medicine
00:19:16 Sex Differences in Brain Aging
00:22:46 Understanding Menopause
00:23:57 Impact of Menopause on the Brain
00:25:36 Research Gap in Menopause and Brain Imaging
00:26:34 Brain Scans and Menopausal Status
00:29:17 Genetic Predisposition to Alzheimer's
00:31:57 Sponsor Break
00:33:05 Back To Show
00:34:31 Apolipoprotein E (APOE) Gene
00:38:28 Menopause and Cognitive Changes
00:49:16 Evolutionary Perspective on Menopause
00:49:35 Brain Scans and Menopausal Changes
00:53:43 Menopause and Brain Changes
00:55:47 Differential Menopausal Experiences
00:56:13 Menopause Types and Health Risks
00:58:02 Hysterectomy and Alzheimer's Risk
00:58:47 Induced Menopause and Cancer Treatments
00:59:52 Understanding Alzheimer's and Dementia
01:02:06 Sponsor Break
01:03:13 Cardiovascular Health and Dementia
01:05:55 Lifestyle and Brain Health
01:11:53 Neuro-Nutrition and Brain Health
01:17:30 Antioxidant-Rich Foods
01:19:35 Supplementation and Nutritional Deficiencies
01:21:57 Antioxidants and Brain Health
01:23:02 Fiber and Hormonal Health
01:24:05 Microbiome and Hormonal Health
01:27:47 Exercise Intensity and Brain Health
01:32:11 Consistency and Long-Term Impact of Lifestyle Changes
01:36:05 Hormone Replacement Therapy and Alzheimer's Risk
01:45:07 Hormone Replacement Therapy
01:46:30 Estrogen Only Formulations
01:49:28 Timing and Type of Hormone Therapy
01:50:26 Brain Scans and Designer Estrogen
01:54:20 Pharmacological Interventions
01:55:41 Diet and Menopause
01:57:10 Sleep and Brain Health
02:06:18 Baseline Testing
02:11:15 Brain Scans and Alzheimer's Prevention Program
02:15:12 Media's Relationship to Health Information
02:16:16 Social Media and Information Accuracy
02:22:08 Scientists and Doctors' Communication Challenges
02:23:22 Science Communication and Public Understanding
02:23:59 Closing Remarks/Credits

* * * * *

NEW TO RICH?
Hi I'm Rich Roll. I'm a vegan ultra-endurance athlete, author, podcaster, public speaker & wellness evangelist. But mainly I'm a dad of four. If you want to know more, visit my website or check out these two the NY Times articles:
bit.ly/otillonyt
bit.ly/vegansglam

I LOVE MAIL! SEND IT HERE:
2630 Conejo Spectrum St.
Thousand Oaks, CA 91320

#richroll #richrollpodcast

All Comments (21)
  • @k.h.6991
    If you get depressed watching this, skip to the end where Lisa discusses what we can do with exercise, diet and sleep to improve brain health and lighten the impact of menopause.
  • @uqox
    This month-old podcast has less than a million views, which is an example of how research and scientific studies on women's health are squeezed out of social media. Here's what I'm going to do: I'm going to forward this video to *every woman I know*, share it in my social circle, and encourage them to share this podcast in their extended social circles. Women are in desperate need of these types of in-depth discussions.
  • This should have thousands of likes! This is the best interview I think I have ever seen on YouTube. It matters to everyone not just women of a certain age. Thank you for doing this interview.
  • I noticed with my Mom, that when she didnt get enough oxygen (ie: move her body to breathe more), her mind would be foggy. I caught on, and would ask her "did you walk the hallway today, Mom?" If she said "no", then I watched the conversation be dull and flat. When she said "yes!", we had a normal, spirited conversation. I'm glad I noticed that connection, as Im 100% convinced that keeping in motion is the KEY to brain health.
  • @kare5252
    As a life long runner 🏃 I noticed that through menopause my strength drastically reduced and injury and joint problems increased very depressing but I moved to weights, strength/ resistance training and it was life changing
  • @WahidaJoosub
    I hate to say this but how much compensation has Lisa Mosconi received from big pharma? I say this because 30 years ago my mom took an all natural product called Wild yam cream -WYC to deal with her menopause issues . Not only did it help her with those issues. Fast forward, my mom lived to age 87 with no complications of dementia, breast cancer or brittle bones. Note my mom was on the WYC for six years. My mom is one out of nine sisters and 6 of her younger sisters ended up with dementia, they were not on the WYC. The only medication my mom required from age 48 to 87 was thyroxine. Lastly my mom never really exercised throughout her life but she cooked almost everyday of her life, enjoyed listening to podcasts, stayed in touch with family overseas by Skype and was always surrounded by people who loved her. Ultimately the WYC has worked for so many women as it's all natural and relatively cheap. Yet few people know about WYC. Could it be because big pharma won't make money. We are of nature so why do we need something not of nature to feel and be healthier????
  • @Bella34544
    Such an important conversation. I work in disability and mental health and a good percentage of the people I work with are woman diagnosed with early onset dementia that is my clients anyway have all been diagnosed in their early 50s. I tell you categorically there is no diagnosis more cruel than an early onset dementia diagnosis and also when diagnosed early the progression tends to be a lot faster - it's absolutely devastating for everyone. Now what for many woman also generally happens in their early 50s? Menopause. The lack of research in this area is just blatant misogyny and sexism. Thank you both for having such an important conversation
  • What I love about this doctor is how she refers to the research as EVER EVOLVING, points out weaknesses in the research she has studied, and ongoingly speaks in terms of "what we know thus far" rather than treating science as ABSOLUTE or DEFINITIVE. Anyone properly trained in research knows that you can verify or falsify a theory but there are no HARD TRUTHS in science. The last few years there has been a great deal of misunderstanding and a lack of scientific humility among well known top doctors. I find hope, anew, in the wonder and promise of doing systematic research using strong methods that can be replicated and build upon the body of knowledge we current have at our disposal. Thank you so much for doing this interview! Never heard of either of you - just happened to stumble across this video! It feels like a God-sent so THANK YOU SO MUCH ❤
  • I enjoyed this video. I started perimenopause at 54. I changed my diet in a very radical way. I flipped to a ketogenic diet. Radical keto. Less than 20 grams of carbs a day. Increased saturated fat. Fat is my fuel. I have reversed the weight gain. Lost it off my midsection. Hot flashes are barely noticeable. Mental acuity is back. Sleeping better. Periods are back. I don’t understand all the connections but when I make sure that I have the fat I need and quality meat, everything in my body celebrates my choices. Cholesterol isn’t something that I need to worry about now. Sugar is my enemy. In all forms. I am thrilled that these issues are coming to light. Each woman needs to find their sweet spot. Some do great on a more veggie based diet. Some do not.
  • @kali542
    I experienced menopause at age 43. I experienced psychosis. I was treated as a psych patient until I demanded estrogen (docs glad to give me lithium but declined over & over to give me HRT). Two days on estrogen patch cured me. I’m 58 now still happy & healthy on estrogen. I have two older sisters who are fully disabled with mental illness and addiction post menopause. They don’t take HRT. The are both forgetting a lot, spell words wrong and have trouble regulating emotions.
  • @sidilicious11
    I’m so glad Dr Lisa and others are doing research into woman’s health. Much more is needed. Eat yr fruits and veggies, sisters!
  • @zoecoote3746
    We need to ask ourselves why so little research has been done in this area seeing as it effects half the population. What a brilliant woman and scientist. She will truely change lives and hopefully change the trajectory of research in women’s health.
  • My mother was diagnosed with Alzheimers at age 59. She died 10 years later.Her neurologist said she did not have the gene for it but that I should make sure I keep a check on my estrogen as I age. I’m 63 now, on HRT, have always exercised and eat clean.
  • @lauradiaz1888
    My mom has Alzheimer’s and she’s 98 years old. She is having issues with UTIs. It is always amazing how little they study women’s health issues. They can send a man to the moon but they cannot figure Oita UTI or Alzheimer’s!
  • @ruth6511
    I am of the generation that were affected by the WHO study so got no HRT and now at 65 it is too late as I am 15 years out from menopause. I am glad for younger women, but sad for my generation that got no help.
  • @vhs10907
    "I'm a scientist and opinion does not matter to me, but numbers do." This statement by Dr Mosconi says so much about listening to her knowledge of what science says. She is a person to listen to.
  • Well I'm 75 and look 60. I swim and golf regularly. I'm a meditator eat one meal a day plus 2 healthy snacks plus vitamins. I've taken also natural HRT for over 35yrs!! I feel great look great and am always have interest in many things. I sell realestate am learning Spanish and the list goes on!!! I give thanks daily.!!!❤❤
  • @agnes77741
    Dear all, I will be 64 next month. Periods stopped at the age of 48. Had hot flashes etc. but it did not bother me till a few months ago. Hot flashes are suddenly making me like fainting, frequent UTI symptoms (pain!) since 3 years, insomnia increased. Decided to ask for HRT last week and started yesterday evening. It is 4 pm now and usually I would have had 10 hot flashes since morning. I had only TWO. Cannot believe it. Life is worth living again.
  • @kellio8087
    Menopause and chronic stress caused me autoimmune disease. My body and brain was going down quick. Doctors didnt help so I did extensive research and chose to do an anti-inflammatory diet, supplementation, and stress elimination. That worked for me.